Cardiac-Vascular Nursing (CVRN) Practice Exam

Which lipid level is typically raised with lipid-lowering therapy?

1. Lipoprotein (a)

2. Triglycerides

3. High density lipoprotein cholesterol

4. Low density lipoprotein cholesterol

The correct answer is: High density lipoprotein cholesterol

High-density lipoprotein cholesterol often referred to as HDL cholesterol, is the lipid level that is typically raised with lipid-lowering therapy. This is particularly significant because HDL is traditionally known as "good" cholesterol. It plays a critical role in removing low-density lipoprotein (LDL) cholesterol from the bloodstream and transporting it to the liver for excretion or reuse. Many lipid-lowering therapies, especially those involving statins, aim not only to lower harmful LDL cholesterol levels but can also have the beneficial side effect of increasing HDL levels. The increase in HDL can contribute to an improved lipid profile and a lower risk of cardiovascular events. In contrast, while triglycerides are commonly targeted and can be decreased with certain therapies, they do not typically increase. Similarly, LDL cholesterol is often the primary target of lipid-lowering medications and is usually reduced rather than raised. Lipoprotein (a) levels are less influenced by standard lipid-lowering treatments. Thus, the increase in HDL cholesterol is a key indicator of successful lipid management in patients undergoing therapy.